Figure 5 - full size

 

Figure 5.
Figure 5. The Pocket Factor, Sphingosine (Shown as a Green Ball-and-Stick Model), in the Binding Pocket of VP1 Located below the External Canyon Region where Host Cell Receptor Binding OccursVP1 and VP3 are shown in blue and red ribbons, respectively. The side chains of the surrounding amino acid residues that have close contacts with sphingosine are shown. The interactions between sphingosine and the amino acid residues are primarily hydrophobic in nature (=<3.6 Å, indicated with dashed lines). Hydrogen bonds are indicated with solid lines.

The above figure is reprinted by permission from Cell Press: Structure (2002, 10, 999-0) copyright 2002.