Figure 5 - full size

 

Figure 5.
Fig. 5. Comparison of the VPA design model to the VPA crystal structure. (A) Shown in blue (asymmetric unit) and cyan (symmetry mate) are the two halves that constitute the VPA crystal structure, and in dark and light orange is the modeled VPA (based on the G55A structure). The overall main-chain rms deviation is 0.40 Å for the blue and orange structures. (B) A close-up of the mutated region.