Figure 5 - full size

 

Figure 5.
Fig. 5. The space-filling drawing of eNOS heme domain with long chain bisisothiourea inhibitor 1,14-BITU modeled in the substrate access channel. The surface residues expected to interact with the ureido of the ligand are labeled.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2001, 276, 26486-26491) copyright 2001.