Figure 5 - full size

 

Figure 5.
Figure 5. Close-up of the active site of urokinase, in ball-and-stick representation, covered by a semi-transparent surface coloured according to the surface electrostatic potential from negative (red) to positive (blue). Also shown is a superposition of amiloride (magenta), EGR-cmk (yellow) and WX293T (cyan) in ball-and-stick representation occupying the different accessible subsites as indicated and discussed in the text. The Figure was produced with MOLSCRIPT, Raster3D and GRASP [Nicholls et al 1991].

The above figure is reprinted by permission from Elsevier: J Mol Biol (2000, 301, 465-475) copyright 2000.