Figure 5. Figure 5 As Fig. 4-. Aromatic residues (here Trp164 is shown) had a `hole' at the centre of the ring in the REFMAC/ARP map (c).
The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2000, 56, 3-0) copyright 2000.