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Figure 4.
Figure 4. View of hapten-binding site. Residues
within 4.2 Å of the hapten are shown. Arg L96 forms
hydrogen bonds with the amide carbonyl oxygen atom,
the pro-R phosphonate oxygen atom, and the bridging
phosphonate oxygen atom of the hapten. Charged
hydrogen bonds are formed between the NH3 group of
Lys H93 and the pro-S phosphonate oxygen atom of the
hapten. The norleucine side-chain of the hapten is sur-
rounded by the hydrophobic residues: Tyr L36, Leu
L46, Leu L89 and Tyr L91. Recognition of the phenyl
ring of the hapten is mediated by the aromatic residues
Phe L98, Tyr L36, Trp H47 and Trp H103.
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