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Figure 4.
Fig. 4. A three-stranded DNA model for homology search
and strand exchange considering the N-S interconversion of sugar
puckers. (a) A molecular model of base pair switch between
single- and double-stranded DNA. The bottom three residues are
in the N-type and the top three residues are in the S-type. Note
that the base pairing is altered by the conversion of sugar
puckers between the N- and S-type. (b) Base rotation schemes for
base pair switching against the interconversion of the sugar
puckers. The bases are rotated toward the minor groove when the
sugar puckers are converted from the N-type (Left) to the S-type
(Right) and toward the major groove with the opposite (S-type to
N-type) conversion.
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