Figure 4 - full size

 

Figure 4.
Fig. 4. Stereo view of the active site of glycosylasparaginase. a, stereo view of superimposition of the active sites between Flavobacterium (shown according to atom type: yellow for carbons, blue for nitrogens, and red for oxygens) and human (shown in gray) GA. Also shown is aspartate in the human enzyme/product structure (13). Dashed lines correspond to the hydrogen bonds described in the human structure. b, the same stereo view of active site in the T152C mutant. The color scheme is the same as the wild type in (a), except that sulfur of the thiol group is shown in green.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (1998, 273, 20205-20212) copyright 1998.