Figure 4.
Figure 4. View of the CCA end of tRNA^Phe in the
active-site cavity of the enzyme. The dashed lines represent the
hydrogen bonds. The letters A and B before residue numbers
indicate the enzyme subunits. The relatively short distance (
vert,
similar 3.8 Å) between the N6 group of A73 (ADE73) and the
phosphate group of C72 (CYT72) indicates that their
intramolecular interaction may help to stabilize the
conformation of the CCA end in a way that resembles tRNA^Gln
[4]. However, the conformation of tRNA^Phe in this region
differs from that of tRNA^Gln. The letters A and B before
residue numbers indicate the enzyme subunits. (Figure was drawn
using MOLSCRIPT [36].)
The above figure is reprinted
by permission from Cell Press:
Structure
(1997,
5,
59-68)
copyright 1997.
vert,
similar 3.8 Å) between the N6 group of A73 (ADE73) and the
phosphate group of C72 (CYT72) indicates that their
intramolecular interaction may help to stabilize the
conformation of the CCA end in a way that resembles tRNA^Gln
[4]. However, the conformation of tRNA^Phe in this region
differs from that of tRNA^Gln. The letters A and B before
residue numbers indicate the enzyme subunits. (Figure was drawn
using MOLSCRIPT [36].)