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Figure 4.
Figure 4. Actin Binding by Destrin(A) Model of the complex
of actin (green) and destrin (yellow) made from coordinates of
the complex of actin and gelsolin segment-1 ([44]). Destrin is
superposed on gelsolin segment-1, as shown in Figure 3A, and
gelsolin segment-1 is hidden. The actin-binding helix is colored
red.(B) Assumed actin-binding residues in destrin (top) and
actual actin-binding residues in gelsolin segment-1 (bottom)
elucidated by [44]. Destrin can be related to Figure 2 by
20° y rotation. The two molecules are oriented by the
superposition described in Figure 3A. Molecular surfaces were
produced using the program GRASP ( [51]) and colored according
to amino acid residue type (yellow, hydrophobic; red, acidic;
blue, basic; white, others) instead of usual surface electric
potential.
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