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Figure 4.
Superposition of the structure of D7 of VEGFR2 with the
structure of D4 of dimeric KIT-SCF complex. Overlay of VEGFR D7
structure (PDB ID code: 3KVQ) and the structure of KIT dimer in
complex with SCF (PDB ID code: 2E9W) (Left). A closer view of
superimposed D7 and D4 regions reveals high similarity in domain
arrangement and homotypic contacts (Right). VEGFR2 D7 is
illustrated in green and the EF loop is in yellow. D4 of KIT is
illustrated in gray and its EF loop is in orange.
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