Figure 4 - full size

 

Figure 4.
Difference free energies are in kcal mol^-1 relative to the DA (27) compound. The individual NH linkages that are changed when switching from DA (27) to MA1 (6), DO (14) or MA2 (22) are numbered as indicated (see text for further details).

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Chem Biol (2009, 5, 407-413) copyright 2009.