Figure 4 - full size

 

Figure 4.
Figure 4. Comparison of NarX[S] and Tar Dimers
(A) Worm representation of the dimeric aspartate receptor Tar, drawn in stereo. Subunits A and B of Tar (Yeh et al., 1996) are colored yellow and blue, respectively.
(B) Worm representation of NarX[s1] dimers in stereo. A “Tar-like” NarX[s] dimer is formed when subunits A (yellow) and B (blue) from NarX[s1](NO[3]) are independently superimposed upon subunits A and B of Tar, respectively. Subunit B from the natural NarX[s] dimer of Figure 1 is shown in gray. The black vertical line represents the quasi two-fold rotation axis of the observed dimer. The red line shows the resulting axis of 9.3° rotation that relates B subunits from the natural, observed NarX[S]dimer and the constructed Tar-like NarX[s] dimer. In the orientation of the molecules shown, the red rotation axis intersects the black rotation axis and is angled approximately 30 degrees above the plane of the figure.

The above figure is reprinted by permission from Cell Press: Structure (2009, 17, 190-201) copyright 2009.