Figure 4 - full size

 

Figure 4.
Detail of the HasA∼HasR∼heme complex showing a putative heme access channel extending from the external medium between L3 and the bent loop L4 to the receptor heme-binding site. HasA and HasR are indicated as a CPK model in red and blue, respectively, except for the heme-coordinating HasR histidines that are colored yellow. The heme is indicated as a wire frame model in green and the Fe^3+ atom as a red sphere.