Figure 4 - full size

 

Figure 4.
(a) F[Ba soak] – F[K] difference map (blue mesh) contoured at 10 showing the two Ba^2+ binding sites. (b) 2F[o] – F[c] ion omit maps of a Ba^2+-soaked crystal contoured at 1.5 . The electron density at the external entrance and site 3 was modeled as Ba^2+ (orange spheres), and water molecules are modeled as red spheres. (c) Ba^2+ (left) and Ca^2+ (right) blocking of ^86Rb influx in liposomes loaded with NaCl.

The above figure is reprinted from an Open Access publication published by Macmillan Publishers Ltd: Nat Struct Biol (2009, 16, 35-41) copyright 2009.