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Figure 4.
FIGURE 4. Interactions of HDAC4cd with inhibitors. A,
interactions of the TFMK (yellow carbons) and HA (green carbons)
with HDAC4; the complex structures have PDB codes 2VQJ and 2VQM,
respectively. Red spheres, water molecules. The surface around
the protein is shown for the TFMK-bound HDAC4cd. B,
superposition of HDAC4cd (cyan) bound to TFMK (sticks and
surface) with HDAC8 (yellow) and homology-modeled HDAC1
(magenta). Residues surrounding the trifluoro group are labeled.
Cyan spheres, C  atoms.
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