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Figure 4.
Figure 4. Comparison of Three Different L11 Orientations in
Complex with PrmA
PrmA and L11 are colored cyan and yellow
in the N-terminal position and blue and orange in the Lys39
position. The Met1 and Lys39 residues and the AdoHcy or AdoMet
cofactors are shown as sticks.
(A) Structure of the L11 N
terminus placed in the active site (complex 2).
(B)
Structure of the noncatalytic L11 orientation (complex 4).
(C) Structure of L11 Lys39 placed in the active site (complex
1).
(D) Comparison of the L11 orientation in the two
catalytic orientations.
(E) Close-up view of the position
of the modified nitrogen atoms of the N-terminal amino group and
Lys39.
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