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Figure 4.
FIGURE 4. Comparison of the structures of the R3/I5 chimera
(blue) and native relaxin-3 (pink). The structures are overlaid
and shown in ribbon representation to illustrate the positions
of the three helical segments. Key amino acids in the
hydrophobic core and active site are shown in ball- and stick
representation and labeled with residue numbers. The INSL5
A-chain is three residues shorter at the N terminus, which
results in a shorter helical segment that is slightly tilted in
relation to the C-terminal helix. In contrast in relaxin-3 the
two A-chain helical segments are roughly parallel.
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