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Figure 4.
Summary of stepping-stone results and working model for Cro
structural evolution. Hypothetical or qualitative aspects are
gray. For example, structures of the common ancestor and Afe01
are known only at the level of general fold either from previous
outgroup analysis (ancestor) or from low-resolution data in the
present study (Afe01). One possible phylogenetic tree topology
is indicated by dashed gray lines. The different colors of the
second subunits shown for Pfl 6 Cro (gold) and λ Cro (red) are
intended to indicate the stronger dimerization of the latter.
(Insets) Residues in the ball-and-socket region of Pfl 6 Cro and
λ Cro.
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