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Figure 4.
Fig. 4. Molecular effects of peptide recognition. (A) The
curvature of the PrgX TPR-like domain increases upon autoinducer
binding. Cyan, apo-PrgX (Protein Data Bank entry 2AXU); magenta,
cCF10:PrgX (Protein Data Bank entry 2AXZ). The pheromone
(yellow) is shown in stick representation. (B) Drawing
illustrating how the increased TPR domain curvature in PapR:PlcR
may rearrange the HTH domains. (Lower) apo-PlcR. (Upper)
PapR:PlcR.
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