Figure 4.
Figure 4. Structure of the HEF2/ERH functional dimer. (A), a
ribbon diagram of the HEF2/ERH dimer. The monomers (red and
blue) are related by a twofold axis and can be generated by the
y, x - z symmetric operation in the crystal lattice. (B), the
-sheets
from the monomers in the dimer form a pseudo- -barrel
(generated by rotate 4A 90°C about the axis in the article
and look-up
).
There is no main chain-main chain hydrogen bond between strand 2
of the two monomers. Tyr79 of both monomers which contribute two
hydrogen bonds (see text) are shown in ball-and-stick. C: a
space-fill representation of the pseudo- -barrel,
viewed from the bottom of the model in panel (B). The cavity
channel at the interface of the two monomers is shown.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2007,
68,
427-437)
copyright 2007.
-sheets
from the monomers in the dimer form a pseudo- 
look-up
).
There is no main chain-main chain hydrogen bond between strand 2
of the two monomers. Tyr79 of both monomers which contribute two
hydrogen bonds (see text) are shown in ball-and-stick. C: a
space-fill representation of the pseudo-