|
Figure 4.
Figure 4. Predicted interactions between Cdk7 (green) and Cdk2
(yellow). (A) Cdk7-F17 faces hydrophobic residues exposed on
Cdk2 surface. Cdk2-L166 is shown in magenta. (B) Interactions of
Cdk2-K9 with Cdk7-P214, D216 and D220 and of Cdk2-Y19 and
Cdk2-K34 with Cdk7-D216. (C) Interactions between Cdk2-K89 and
Cdk7-D104, Cdk2-R297 and Cdk7-N311 and between the C-terminal
carboxylate of Cdk2 and Cdk7-S106. (D) Cdk2-K88 and R200
interact with Cdk7-E20. Cdk7-F17 is shown together with its
contacts with Cdk2-R200 and P204.
|
