Figure 4.
FIGURE 4. Inhibition of t-PHD2 by the TCAIs (at 1 mM final
concentration). No inc refers to the assay without a
preincubation step; 1hrinc refers to a 1-h preincubation of
t-PHD2 with iron, buffer, and compound (where applicable), and
1hrinc + asc refers to a 1-h preincubation of t-PHD2 with iron,
buffer, and ascorbate.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2007,
282,
3293-3301)
copyright 2007.