Figure 4 - full size

 

Figure 4.
FIGURE 4. Inhibition of t-PHD2 by the TCAIs (at 1 mM final concentration). No inc refers to the assay without a preincubation step; 1hrinc refers to a 1-h preincubation of t-PHD2 with iron, buffer, and compound (where applicable), and 1hrinc + asc refers to a 1-h preincubation of t-PHD2 with iron, buffer, and ascorbate.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2007, 282, 3293-3301) copyright 2007.