Figure 4.
Fig. 4. Stereoview of active sites. (A) Overlay of the
active sites of Cu(II) AZAMI (green), AZAMI-F (gray), AZ
(purple), and AMI (yellow). The side chains of the coordinating
residues and the amino acids on either side of the N-terminal
His ligand are shown as stick models, copper atoms as spheres,
and the backbone of the C-terminal ligand-containing loops as C^
traces. The residues
are labeled as in AZ. (B) Overlay of the active sites of the
Cu(I) form of AZAMI-F at pH 8 (slate) and pH 6 (cyan) is shown.
The second conformation of the copper ion and His-115 at pH 6
are colored green. The figure was prepared by using the program
PYMOL (6).
traces. The residues
are labeled as in AZ. (B) Overlay of the active sites of the
Cu(I) form of AZAMI-F at pH 8 (slate) and pH 6 (cyan) is shown.
The second conformation of the copper ion and His-115 at pH 6
are colored green. The figure was prepared by using the program
PYMOL (6).