Figure 4.
FIGURE 4. gD mimics BTLA. a, molecular surface of HVEM
(CDR1 white; CRD2, light blue; CRD3, blue) is shown with C- renderings of BTLA.
HVEM residues crucial for BTLA affinity (P17, V36, and Y23) are
colored red and labeled. b, molecular surface of HVEM colored as
in a with C- rendering of gD (N- and
C-terminal extensions, yellow; Ig domain, green). HVEM residues
crucial for gD affinity (C37 and Y23 (28)) are colored red and
labeled. c, sequence of the structurally similar short -strands
in BTLA and gD that bind HVEM.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2005,
280,
39553-39561)
copyright 2005.
renderings of BTLA.
HVEM residues crucial for BTLA affinity (P17, V36, and Y23) are
colored red and labeled. b, molecular surface of HVEM colored as
in a with C- 
-strands
in BTLA and gD that bind HVEM.