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Figure 4.
Fig. 4. Arginase I-ABH complexes. Summary of average
intermolecular interactions in the human arginase I-ABH complex
(gray numbers) and the rat arginase I-ABH complex (orange
numbers). Note that the higher resolution of the human arginase
I-ABH structure allows for more accurate hydrogen bond distance
measurements. Manganese coordination interactions are indicated
by green dashed lines, and hydrogen bonds are indicated by black
dashed lines. Several slightly shorter and stronger
enzyme-inhibitor hydrogen bond interactions are observed in the
human enzyme, consistent with its enhanced affinity for ABH
(Table 2).
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