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Figure 4.
Figure 4. View of the Novel Binding Site in a Shallow
Groove at the Interface of Two B Subunits of LCTBK(A) Overview
picture. The blood group A pentasaccharide is shown in stick
representation; the GM1 pentasaccharide is indicated by white
spheres. (Inset: positions of the novel binding site and the GM1
binding site within the B-pentamer, marked with red and white
circles, respectively). Please note that the carbohydrate ligand
is only displayed for one of the five equivalent binding sites
within the B-pentamer.(B) Close-up view of the blood group A
binding site, featuring the two separate water networks (figure
generated with Swiss-PdbViewer and POV-Ray).
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