Figure 4 - full size

 

Figure 4.
Figure 4: Omit-annealed F[o] - F[c] map around AMPPCP at 5 sigma-(a) and the hydrogen-bonding network around AMPPCP (b). AMPPCP is shown in ball-and-stick representation; the N- and P-domains are coloured light green and orange, respectively. Light-green broken lines in b show likely hydrogen bonds. A part of the N-domain is removed for clarity. Small spheres represent Mg^2+ (green) and two water molecules (red), which coordinate to the Mg^2+, together with -phosphate, carboxyl groups of Asp 351 and Asp703, and a carbonyl group of Thr 353 (orange broken lines in a and dark-green lines in b).

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2004, 430, 529-535) copyright 2004.