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Figure 4.
Figure 4. Comparison of the Histone Domain of Sos with the
Structures of Various Histone ProteinsSuperpositions were
generated by TOP3D (Lu, 2000). The histone domain of Sos is
shown in gray. The darker gray represents the C-terminal H2A
homology region. Rms deviations for the Ca backbone atoms
between structures being compared are indicated. Alignment with
the nucleosomal core histone dimers H2A/H2B (A) and H3/H4 (B)
are shown. H2A is colored in light green, H2B in dark green. H3
and H4 are shown in orange and red, respectively (PDB code:
1KX5; Davey et al., 2002). (C) Alignment with Methanopyrus
kandleri histone (PDB code: 1F1E; Fahrner et al., 2001).
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