Figure 4.
Figure 4 Comparison of active-site binding region of hDHFR with
NADPH and antifolate (1) for the R3 lattice (cyan) and for the
P4[3]2[1]2 lattice (yellow). Also shown is F31A hDHFR-TMQ
(violet). Models were produced with SETOR (Evans, 1993[Evans, S.
V. (1993). J. Mol. Graph. 11, 134-138.]).
The above figure is reprinted
by permission from the IUCr:
Acta Crystallogr D Biol Crystallogr
(2003,
59,
1603-1609)
copyright 2003.
