Figure 4.
Figure 4. Binding orientation of
3,4-dihydropyridol[3,2-d]pyrimidine and 2(1H)-quinazolinone to
p38 .
Surface representation of the inhibitor-binding site: the
linker region is red, the glycine-rich loop blue. Compounds 2
(green)24 and 4 (magenta) are shown with their molecular surface
outlined.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(2003,
10,
764-769)
copyright 2003.
.
Surface representation of the inhibitor-binding site: the
linker region is red, the glycine-rich loop blue. Compounds 2
(green)24 and 4 (magenta) are shown with their molecular surface
outlined.