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Figure 4.
FIG. 4. Schematic of the main channel illustrating the
presence of a negative charge (in green) on the side chain of
Glu181 and a positive charge (in green) on the heme iron and the
effect of the electrical potential between these two charges on
the electrical dipoles of water in the channel and active site.
The orientation of the electrical dipoles is indicated by the
green arrow over each H[2]O. The location of the water molecules
are those in subunit A of variant D181E.
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