Figure 4 - full size

 

Figure 4.
Figure 4. (a) Resonance forms (A, B) for the lowest energy (non-bind- ing) conformation of the benzi- midazole scaffold. Structure C represents the conformer and tauto- mer for bound benzimidazoles. (b1) Resonance forms for the lowest energy (non-binding) conformation of the 6-chlorobenzimidazole scaffold (D, E). Structure F rep- resents the conformer and tautomer for bound 6-chlorobenzimidazoles. (b2) Resonance forms for bound 6-chlorobenzimidazoles.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2003, 329, 93-0) copyright 2003.