Figure 6 - full size

 

Figure 6.
Figure 6. Stereo View of the Contacts between the CR1 Loop of EGFR Molecule A with CR1 of EGFR Molecule B in the Back-to-Back Dimer InterfaceCR1 loop of EGFR molecule A is shown in orange, and CR1 of EGFR molecule B is in gray. Interchain hydrogen bonds are drawn in black along with the hydrogen bond from Asn247 of molecule A (not labeled), which appears to stabilize the loop tip conformation. The single letter code and residue number is used for amino acid residues. The dimer axis lies vertically at the left at H280.

The above figure is reprinted by permission from Cell Press: Cell (2002, 110, 763-773) copyright 2002.