Figure 4.
Figure 4 Stereoview of the electron density (2F[o] - F[c], 1
)
(blue) and (F[o] - F[c], -3 )
(red) that results from phases of conformer 1 only, showing the
fit of the inhibitor (2) in conformation 1 (red) and
conformation 2 (yellow) in pcDHFR-NADP+ ternary complex. Diagram
produced with CHAIN (Sack, 1988[Sack, J. S. (1988). J. Mol.
Graph. 6, 244-245.]).
The above figure is reprinted
by permission from the IUCr:
Acta Crystallogr D Biol Crystallogr
(2002,
58,
1393-1399)
copyright 2002.
)
(blue) and (F[o] - F[c], -3