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Figure 4.
Figure 4. Comparison of the carbamoyl phosphate binding
site between the B. fragilis transcarbamylase-like structure and
human OTCase. (a) Putative carbamoyl phosphate-binding site in
the B. fragilis protein. The phosphate group and two active-site
water molecules are shown as a ball-and-stick model. (b)
Carbamoyl phosphate-binding site in human OTCase.[42] CP is
shown as a thick ball-and-stick model. The phosphate group in
the B. fragilis protein is located in the same position as the
phosphate moiety of CP in human OTCase and interacts with the
protein in a similar way. Two water molecules occupy the
respective positions of the carbamoyl nitrogen and oxygen atoms
of CP. The Figure was drawn with MOLSCRIPT.[41]
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