Figure 4.
Figure 4 Interaction of EF-Tu and aa-tRNA with the ribosome. (A
and B) Ribbons representation of the docked EF-Tu and aa-tRNA
within the ternary complex. (C and D) Focus on the interaction
between the -sarcin−ricin
loop (SRL) and the effector loop within domain I of EF-Tu
(cyan). In (C) the coordinates of the whole ternary complex from
T.aquaticus with a GTP analog (Nissen et al., 1995) were used
for the fitting, while in (D) the crystal structure of EF-Tu
from E.coli bound to GDP (Song et al., 1999) was used.
Orientation of the ribosomes for (A) and (B) are shown as
thumbnails on the left. Labeling is the same as in Figure 5.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2002,
21,
3557-3567)
copyright 2002.
-sarcin−ricin
loop (SRL) and the effector loop within domain I of EF-Tu
(cyan). In (C) the coordinates of the whole ternary complex from
T.aquaticus with a GTP analog (Nissen et al., 1995) were used
for the fitting, while in (D) the crystal structure of EF-Tu
from E.coli bound to GDP (Song et al., 1999) was used.
Orientation of the ribosomes for (A) and (B) are shown as
thumbnails on the left. Labeling is the same as in Figure 5.