Figure 4 - full size

 

Figure 4.
Figure 4 Different (putative) dimeric forms of lipocalins. Disulfide bridges are indicated in yellow; free cysteines are indicated in green. The dimers were automatically generated from the original PDB entries by the PQS server ([201]http://pqs.ebi.ac.uk ). (a) Bovine odorant-binding protein ([202]1obp ; Tegoni et al., 1996[203] [Tegoni, M., Ramoni, R., Bignetti, E., Spinelli, S. & Cambillau, C. (1996). Nature Struct. Biol. 3, 863-867.]-[204][bluearr.gif] ), buried surface area 2399.7 Å2. (b) Porcine BLG ([205]1exs ; this paper), buried surface area 1757.7 Å2. (c) Major horse allergen (1ew3; Lascombe et al., 2000[206] [Lascombe, M. B., Gregoire, C., Poncet, P., Tavares, G. A., Rosinski-Chupin, I., Rabillon, J., Goubran-Botros, H., Mazie, J. C., David, B. & Alzari, P. M. (2000). J. Biol. Chem. 275, 21572-21577.]-[207][bluearr.gif] ), buried surface area 1023.3 Å2. (d) Porcine odorant-binding protein ([208]1e06 ; Spinelli et al., 1998[209] [Spinelli, S., Ramoni, R., Grolli, S., Bonicel, J., Cambillau, C. & Tegoni, M. (1998). Biochemistry, 37, 7913-7918.]-[210][bluearr.gif] ), buried surface area 848.2 Å2. (e) Nitrophorin 4 ([211]1eqd ; Weichsel et al., 2000[212] [Weichsel, A., Andersen, J. F., Roberts, S. A. & Montfort, W. R. (2000). Nature Struct. Biol. 7, 551-554.]-[213][bluearr.gif] ), buried surface area 789.1 Å2. (f) Bovine BLG ([214]1b0o ; Wu et al., 1999[215] [Wu, S. Y., Perez, M. D., Puyol, P. & Sawyer, L. (1999). J. Biol. Chem. 274, 170-174.]-[216][bluearr.gif] ), buried surface area 484.1 Å2. The figure was produced with Weblab Viewer Lite (MSI).

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2002, 58, 480-486) copyright 2002.