Figure 4.
Figure 4. Superposition of the wild-type pH 8 (T-state) and pH
4.8 (R-state) models at the molecular interface shows how the
change in the position of residue E227 affects its interaction
with R64 .
The pH 8 model is shown with light bonds and pH 4.8 model with
dark bonds. In the R-state model, E227 forms ion pair
interactions across the molecular interface with R48 and
R64 .
R64 also
forms an interaction with D231. In the T state, interactions
with E227 are not observed. R64 only
interacts with D231, and R48 is
disordered.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2002,
46,
321-329)
copyright 2002.
.
The pH 8 model is shown with light bonds and pH 4.8 model with
dark bonds. In the R-state model, E227 forms ion pair
interactions across the molecular interface with R48