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Figure 4.
Figure 4. The Metal Binding Site in MMCE(a) The difference
electron density peak for the bound Co2+ ion is shown, in
coordinating distance of the side chains of His12, Gln65, His91,
and Glu141. Virtually no movement of these coordinating groups
occurs on metal complexation to the apo-protein.(b) The metal
sites of MMCE and GLO are superimposed using only the Ca atoms
of the two proteins for superposition. For MMCE, the polypeptide
backbone is in gray, with side chains and the Co2+ ion in blue;
for GLO, the polypeptide backbone is in black, with side chains
in red (monomer A) and gold (monomer B), and the Zn2+ ion in red
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