Figure 4 - full size

 

Figure 4.
Fig. 4. Protein ligands for class I molecules interact with different surfaces. Superposition of class I/receptor complexes for which the structure is known reveals that the five class I ligand types bind at distinct locations. Class I interaction surfaces are colored according to each ligand: US2 (magenta), Ly49A (green), B7 TCR (blue), KIR2DL1 (red), CD8 (cyan). Equivalent C atoms for class I heavy chain were used to generate pairwise superpositions. HLA-A2 heavy chain (yellow), [2]-microglobulin (gray), US2 (magenta), Tax peptide (green).