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Figure 4.
Figure 4. The CoA binding mode observed in the FabH+CoA
structure. (a) The electron density for the bound CoA molecule
contoured at 1.0 s. Atoms are colored in the same way as in
previous figures. (b) Stereoview of the CoA molecule in the FabH
active site tunnel. Amino acid residues are labeled and hydrogen
bonds are shown with broken lines. CoA is drawn in thicker lines
with the carbon atoms in purple. (c) Stereoview of Arg42 and its
role in stabilizing helices La5 and La2. Hydrogen bonding
interactions are shown in red dashed lines. The adenine of CoA
is shown with magenta bonds.
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