Figure 4.
Figure 4 Space-filling models of human -thrombin
and haemadin, showing the surface potential of the two
molecules. Positive charges are displayed in blue, negative
charges in red, with darkest blue and red colours corresponding
to electrostatic potentials beyond -10 and +10 kT/e,
respectively. The plot was prepared with GRASP (Nicholls et al.,
1993). The thrombin component (B) is shown in the standard
orientation, while haemadin (A) is rotated along the y-axis to
present the thrombin binding surface to the viewer. Some of the
residues of the interacting interfaces are labelled.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2000,
19,
5650-5660)
copyright 2000.
-thrombin
and haemadin, showing the surface potential of the two
molecules. Positive charges are displayed in blue, negative
charges in red, with darkest blue and red colours corresponding
to electrostatic potentials beyond -10 and +10 kT/e,
respectively. The plot was prepared with GRASP (Nicholls et al.,
1993). The thrombin component (B) is shown in the standard
orientation, while haemadin (A) is rotated along the y-axis to
present the thrombin binding surface to the viewer. Some of the
residues of the interacting interfaces are labelled.