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Figure 4.
Figure 4. The RING Domain of c-Cbl and the HECT Domain of
E6AP Recognize the Same Structural Elements of UbcH7The H1
helix, L1, and L2 loops of UbcH7 are colored in green, red, and
yellow, respectively. Portions of the molecular surfaces of the
RING domain of c-Cbl (left) and the HECT domain of E6AP (right)
are shown as a white net. The Phe-63 residue of UbcH7 inserts
its side chain into a groove formed by the E3 in both cases.
(Prepared with the program GRASP; [25])
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