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Figure 4.
Fig. 4. Binding of Man(  1-3)Man(
1-O)Me in
the hydrophobic subsite. a, superposition of M3M·ConA (
light gray) and 4'-methylumbelliferyl- -D-glucopyranoside
(black). The O-3-linked mannose of M3M occupies the same subsite
as the aglycon methylumbelliferyl of the substituted glucose.
The conformations around the glycosidic linkages are similar. b,
the hydrophobic character of the M3M subsite. M3M is shown as a
ball-and-stick model. The van der Waals surface of ConA is
colored according to residue properties: hydrophobic (brown),
basic (blue), acidic (red), other polar residues (light green),
or glycine (yellow). This figure was created using GRASP (49).
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