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Figure 4.
Figure 4. Cartoon representation of ligand binding to four
α/β-barrel PEP/pyruvate-utilizing enzymes. The β/α motifs
are numbered sequentially. For PEP mutase, helix 8 is colored
yellow because it is contributed by a neighboring molecule. The
loop connecting the β/α motif 3 in pyruvate kinase corresponds
to a whole domain and is shown as a broken yellow line. Motifs 1
and 2 in enolase do not obey the classical topology of β/α
motifs. Residues that interact with PEP/pyruvate/oxalate are
colored red. Residues that interact with Mg^2+ are colored blue.
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