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Figure 5.
Figure 5. Predicted Structural Effects of the Caspase 8
Cleavage of BIDA ribbon diagram of (a) the full-length p22 BID
versus (b) the p15 tBID model (flexible loop BC and amino
terminus not shown). An analysis of the exposed hydrophobic
surface for (c) BID and (d) the tBID model presented in the same
orientation as in (a) and (b). Hydrophobic surfaces were
generated using GRASP ([44]); here the gray and yellow indicate
hydrophobic and hydrophilic surfaces, respectively.
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