Figure 4 - full size

 

Figure 4.
Figure 4 Ribbon diagram comparing the subunit folds of T4 CH (left) and E.coli TS (right). The structurally similar parts are colored in blue and the remaining parts in orange. The catalytically important residues (Glu60, Cys148 and Asp179 in T4 CH; Glu58, Cys146 and Asn177 in E.coli TS) are shown in green. The substrates dCMP in T4 CH and dUMP in E.coli TS are drawn in deep blue and the cofactor analog CB3717 bound to E.coli TS is in magenta. This figure was drawn by MOLSCRIPT (Kraulis, 1991) and RASTER 3D (Merritt and Murphy, 1994).

The above figure is reprinted from an Open Access publication published by Macmillan Publishers Ltd: EMBO J (1999, 18, 1104-1113) copyright 1999.