Figure 3 - full size

 

Figure 3.
Fig. 3. Relationship of the two t-butanol-binding sites to groups at the active site. A, in the free enzyme, t-butanol occupies the distal portion of the substrate-binding site. B, in the enzyme-substrate complexes, t-butanol occupies an auxiliary site adjacent to the distal portion of the substrate-binding site, further removed from the iron.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (1998, 273, 34887-34895) copyright 1998.