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Figure 3.
Figure 3. Secondary structure elements in hPEBP. (a) The
putative dimer of hPEBP formed by the two molecules in the
asymmetric unit of the crystal. Also shown (arrow) is the
approximate direction of the dipole moment for the hPEBP dimer,
which suggests an orientation for the oligomer to interact with
the membrane. The molecules of cacodylate present in the
ligand-bound structure are shown in CPK representation. (b)
Schematic topology diagram illustrating the arrangement of
secondary structure in the hPEBP monomer. β Strands (shown in
cyan) are labelled with lower-case letters and correspond to
immunoglobulin/fibronectin type III conventions, as discussed in
the text; α helices (shown in red) are labelled with upper-case
letters. (The figures were prepared using the program MOLSCRIPT
[32] and rendered using Raster3D [33].)
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